Figure 1

Comparison of faecal microbiota diversity in the healthy group and disease groups. (A) Principal coordinate analysis based on the weighted UniFrac distances as β-diversity. The blue and red dots (triangle: chronic enteropathy [CE]; square: small-cell lymphoma [SCL]) correspond to healthy dogs and dogs with disease, respectively. Weighted UniFrac distances were compared using permutational multivariate analysis of variance between healthy and disease groups. (B) Three indices (Faith’s PD, observed amplicon sequence variants and Shannon index) as α-diversity (upper: main analysis; lower: subgroup analysis). The P value of the Kruskal–Wallis test is indicated by the top dashed line, while the solid line represents the P value of post hoc multiple comparisons using Dunn’s test with Bonferroni adjustment.