Figure 5
From: miR-27a-3p promotes inflammatory response in infectious endophthalmitis via targeting TSC1
TSC1 inhibition promoted inflammation in vitreous samples. (A) RT-qPCR analysis of relative expression of TSC1; (B) H&E staining of retina tissues in each group; The concentrations of (C) IL-1Ī±, (D) IL-1Ī², (E) IL-6, (F) IL-8, (G) IL-10, (H) TNF-Ī±, (I) IFN-Ī³, and (J) GM-CSF in vitreous samples were measured by ELISA. (***pā<ā0.001 vs. the control group; ###pā<ā0.001 vs. the LPS group; &&&pā<ā0.001 vs. the LPSā+āAntagomiR-27a-3pā+āLV-sh-NC group). TSC1 tuberous sclerosis complex 1; RT-qPCR reverse transcription-quantitative polymerase chain reaction; H&E Hematoxylināeosin; IL interleukin; TNF-Ī± tumor necrosis factor Ī±; IFN-Ī³ interferon-Ī³; GM-CSF granulocyteāmacrophage colony-stimulating factor; ELISA enzyme-linked immunosorbent assay; LPS lipopolysaccharide; LV lentivirus; sh-, short hairpin.
