Table 1 Clinical characteristics of the study population.
From: miR-27a-3p promotes inflammatory response in infectious endophthalmitis via targeting TSC1
Characteristic | Controls (n = 23) | Infectious endophthalmitis (n = 31) miR-27a-3p | p-value | |
|---|---|---|---|---|
High (n = 15) | Low (n = 16) | |||
Age (yr), median ± SD | 41.17 ± 15.44 | 55.73 ± 18.66 | 47.88 ± 16.87 | 0.228 |
Gender (male:female), n | 13:10 | 7:8 | 10:6 | 0.376a |
Diagnosis, n | – | |||
Postoperative (cataract surgery) | – | 8 | 7 | |
Traumatic | – | 3 | 5 | |
Endogenous | – | 4 | 4 | |
Macular hole/macular edema | 20 | – | – | |
Rhegmatogenous retinal detachment | 3 | – | – | |
Initial visual acuity (logMar) | – | |||
0.6–2 | 10 | 8 | 4 | |
2.6 | 8 | 3 | 4 | |
3.2 | 5 | 4 | 8 | |
Final visual acuity (logMar) | – | |||
0.4–1.3 | 7 | 5 | 3 | |
2–2.9 | 7 | 6 | 5 | |
3–3.2 | 9 | 4 | 8 | |
Evisceration, n | – | – | – | |
Inflammation/polymorphs (vitreous), n | – | |||
0–3 | – | 3 | 5 | |
0–5 | – | 3 | 6 | |
0–10/0–plenty | – | 9 | 5 | |
Surgical interventions, n | – | |||
< 2 | 21 | 4 | 9 | |
≥ 2 | 2 | 11 | 5 | |
Pathogenic microorganisms | – | |||
Gram positive | – | 9 | 12 | |
Gram negative | – | 1 | 0 | |
Fungal | – | 5 | 4 | |
