Table 2 List of the up-regulated genes in common in all the edited clones versus the parental line. Fold changes (Log2) and adjusted p-value are indicated.

From: Correction of exon 2, exon 2–9 and exons 8–9 duplications in DMD patient myogenic cells by a single CRISPR/Cas9 system

Name

Dup2 clone 7 vs Dup2

Dup2–9 clone 14 vs Dup2–9

Dup8-9 clone 12 vs Dup8-9

Fold change (Log2)

p-value

Fold change (Log2)

p-value

Fold change (Log2)

p-value

MAN1C1

0.84

0.004762

0.74

0.000139

0.61

0.049479

NEGR1

1.25

1.69E−13

1.30

1.98E−28

0.98

1.07E−13

MAPK10

1.12

1.56E−07

0.65

0.000104

1.73

8.29E−06

RNF150

0.68

0.013628

1.07

4.67E−15

2.28

3.15E−09

PTCHD4

0.92

0.000939

0.58

0.002661

0.67

0.002589

COL19A1

0.90

5.44E−08

1.09

1.39E−34

3.04

4.97E−06

BAIAP2L1

2.27

1.09E−27

1.39

4.57E−16

1.59

6.61E−05

MSR1

1.25

0.005971

1.10

6.42E−10

1.10

4.05E−05

LINC01239

1.10

5.03E−05

0.85

0.000106

1.60

0.000413

RTKN2

1.29

6.31E−09

0.75

8.44E−05

2.36

4.02E−15

DNMBP

1.00

1.03E−14

0.52

0.001605

1.39

7.59E−18

CDKN1C

0.99

1.45E−05

0.69

8.76E−08

1.60

3.44E−08

ARHGAP20

1.23

3.37E−09

0.81

3.63E−08

1.00

2.54E−05

METTL7A

1.03

0.001604

0.78

0.000394

1.47

0.000928

SLITRK5

1.90

8.22E−19

0.78

5.90E−07

1.98

1.07E−22

ADGRG1

0.95

2.72E−05

0.70

1.67E−10

1.98

0.000683

HSD11B2

1.32

9.62E−14

0.91

1.59E−10

1.35

1.82E−05

ABCA8

1.41

2.59E−13

0.68

1.70E−05

0.53

0.001833

NOL4L

0.91

0.005077

0.53

0.041591

1.29

2.30E−07

KREMEN1

1.26

2.45E−07

0.59

9.99E−08

0.84

4.43E−07

DMD

2.02

3.82E−37

2.47

6.40E−200

1.78

7.68E−41

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