Table 1 SIEGA features and description.

From: The integrated genomic surveillance system of Andalusia (SIEGA) provides a One Health regional resource connected with the clinic

Feature

Description

Interface

With different subsections to facilitate the analysis:

Sample Status information on each sample, including the quality control status

Metadata information needed for sample and study traceability

Application control information on the status and results of the pipeline of analysis

Results detailed overview of the results obtained for any sample

Flexible Table allows merging of any variety of result tables, metadata, or statuses for complex representation of results

User management

Access permission structure allowing users and group with many options to share data across users and groups

Data upload

Comma-separated values (CSV) file for metadata

Fastq R1 and R2 files for each sample

Data processing and quality control

Quality control information on the result of each application is reportes (green: good, yellow: fair, red: poor)

Data traceability

Each sequenced sample has a distinctive identifier, used for associating relevant metadata

Automatic reporting

A report is generated for each sample including:

MLST

cgMLST

Serotyping outcomes

Antimicrobial resistance genes

Virulence genes

Plasmids

A phylogenetic tree with the most related samples

Customized phylogenetic analysis

All existing tables can be combined using a wizard (flexible table) that enables the creation of combined tables with relevant data for each case, from which phylogenetic trees can be generated

Alert system

Automatic alerts based on various criteria can be established:

Allelic distances

Specific sequence type match

Serotype predicted

Presence of antimicrobial resistance genes

Presence of virulence genes