Table 2 Hazards ratio of outcomes regarding surgery versus no surgery as initial treatment for patients with intrahepatic cholangiocarcinoma during 2004–2018.
From: Prognostic factors in patients with intrahepatic cholangiocarcinoma
Outcome variables | Unmatched (before propensity score matching) | Matched (after propensity score matching) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Surgery | Surgery versus no surgery | Surgery | Surgery versus no surgery | |||||||||
No (N = 5377) | Yes (N = 2563) | No (N = 969) | Yes (N = 969) | |||||||||
n (%) | n (%) | Unadjusted HR | P | Adjusted HR | P | n (%) | n (%) | Unadjusted HR | P | Adjusted HR | P | |
Overall survival | 1335 (24.8) | 1075 (41.9) | 0.96 (0.88–1.03) | 0.257 | 0.65 (0.60–0.71) | < 0.001 | 221 (22.8) | 341 (35.2) | 0.92 (0.78–1.09) | 0.348 | 0.69 (0.62–0.78) | < 0.001 |
Cancer-specific survival | 2515 (46.8) | 1543 (60.2) | 1.21 (1.13–1.29) | < 0.001 | 0.60 (0.55–0.66) | < 0.001 | 390 (40.2) | 512 (52.8) | 1.06 (0.93–1.21) | 0.393 | 0.65 (0.57–0.74) | < 0.001 |
Disease-free survival | 148 (2.8) | 1067 (41.6) | 0.25 (0.21–0.30) | < 0.001 | 0.45 (0.42–0.49) | < 0.001 | 44 (4.5) | 295 (30.4) | 0.34 (0.24–0.46) | < 0.001 | 0.54 (0.48–0.60) | < 0.001 |
Local recurrence | 224 (4.2) | 1330 (51.9) | 0.24 (0.21–0.28) | < 0.001 | 0.38 (0.35–0.41) | < 0.001 | 59 (6.1) | 397 (41.0) | 0.28 (0.21–0.37) | < 0.001 | 0.46 (0.41–0.51) | < 0.001 |