Table 1 Patient characteristics for all patients and the patient groups “Rejected IE”, “Possible IE” and “Definite IE”.

From: Evaluating the Duke Criteria for infectious endocarditis in a single-center retrospective study

Patient characteristics

Overall (n = 163)

Rejected IE (n = 15)

Possible IE (n = 19)

Definite IE (n = 129)

p value1

Gender

 Male, n (%)

118 (72.4)

12 (80)

10 (52.6)

96 (74.4)

0.121

Age (years)

 Total, median (IQR)

68.6 (58–77.6)

73.7 (65.8–80.7)

75.1 (67.7–88.1)

65.9 (55.2–75.6)

0.007

Prosthetic valve before presentation

 Total, n (%)

46 (28.2)

5 (33.3)

4 (21.1)

37 (28.7)

0.7

CIED before presentation

 Total, n (%)

39 (23.9)

5 (33.3)

6 (31.6)

28 (21.7)

0.42

 Pacemaker, n (%)

22 (13.5)

3 (20)

4 (21.1)

15 (11.6)

 

 Defibrillator, n (%)

8 (4.9)

1 (6.7)

2 (10.5)

5 (3.9)

0.687

 CRT-D, n (%)

9 (5.5)

1 (6.7)

0 (0)

8 (6.2)

 

Diagnostic delay after presentation

 Days elapsed until final diagnosis, median (IQR)

4 (2–9)

13 (4.8–25.3)

4 (2–10)

3 (2–7)

0.010

 Hospitalization time, Median (IQR)

23 (16–39)

21 (16–33)

19 (10–39)

25 (18–40)

0.208

Intensive care treatment

 Patient with intensive care treatment, n (%)

79 (48.5)

5 (33.3)

7 (36.8)

67 (51.9)

0.261

 Length of the stay (days), median (IQR)

11 (5–17)

19 (8.5–36)

6 (2–19)

10 (5–16)

0.37

In-hospital mortality

 Total, n (%)

30 (18.4)

4 (26.7)

4 (21.1)

22 (17.1)

0.58

 Day of death after admission2, median (IQR)

20 (10.75–33)

27 (15.8–72.8)

13.5 (4.8–47.8)

20 (10.8–32.3)

 
  1. P value1 refers to the comparison between the groups “Rejected IE”, “Suspected IE”, Definite IE”. For nominal variables the Exact Fisher-Freeman-Halton-Test respectively the Chi-Square-Test was used and for metric variables the Kruskal–Wallis-Test was used.
  2. 2The p value of 0.007 refers to the age of the different groups.
  3. In hospital mortality only counts patients that died during the stay in our hospital. Survival is compared via log rank test in Fig. 1.
  4. IE infective endocarditis, IQR interquartile range, n number of patients, CIED cardiac implantable electronic device, CRT-D cardiac resynchronization therapy.
  5. Significant values are in bold italic.