Table 3 Validity of the ESC 2015 Duke Criteria in NVE (n = 84) and PVE (n = 33) of the DIE group.

From: Evaluating the Duke Criteria for infectious endocarditis in a single-center retrospective study

Parameter

Native valve endocarditis (n = 84)

Prosthetic valve endocarditis (n = 33)

p value1

Gender

 Male, n (%)

60 (71.4)

27 (81.8)

0.347

Age (years)

 Total, median (IQR)

65.3 (51.4–73.7)

70 (59.9–80)

0.062

Rate of positive Duke-Criteria, n (%)

 Imaging positive for IE

Day of admission

35 (41.7)

13 (39.4)

1.000

Until discharge

77 (91.7)

31 (93.9)

1.000

 Blood cultures positive for IE

Day of admission

33 (39.3)

17 (51.5)

0.299

Until discharge

56 (66.7)

24 (72.7)

0.660

 Fever > 38 °C

Day of admission

42 (50)

16 (48.5)

1.000

Until discharge

52 (61.9)

18 (54.5)

0.532

 Vascular phenomena

Day of admission

23 (27.4)

12 (36.4)

0.374

Until discharge

43 (51.2)

23 (69.7)

0.097

 Immunological phenomena

Day of admission

3 (3.6)

1 (3)

1.000

Until discharge

8 (9.5)

5 (15.2)

0.513

 Predisposition

Day of admission

34 (40.5)

33 (100)

 < 0.001

Until discharge

34 (40.5)

33 (100)

 < 0.001

 Microbiological evidence

Day of admission

8 (9.5)

2 (6.1)

0.723

Until discharge

12 (14.3)

4 (12.1)

1.000

Pre-existing cardiovascular disease, n (%)

 Cardiac arrhythmia

 

38/84 (45.2)

20/33 (60.6)

0.154

 CAD

 

31/84 (36.9)

17/33 (51.5)

0.210

 Diabetes mellitus

 

24/84 (28.6)

11/33 (33.3)

0.657

 Diabetic complications

 

13/19 (68.4)

2/7 (28.6)

0.095

 Hypertonia

 

50/84 (59.5)

23/33 (69.7)

0.397

 History of HF

 

34/84 (45.3)

19/28 (67.9)

0.049

 Open Wounds

 

9/84 (10.7)

4/33 (12.1)

1.000

 PAD

 

7/84 (8.3)

7/33 (21.2)

0.064

 History of MI

 

14/84 (16.7)

5/33 (15.2)

1.000

 Structural heart disease

 

5/84 (6)

0/33 (0)

0.320

  1. P value1 refers to the p value of the groups “NVE”, “PVE”, compared by Fisher’s Exact Test or Mann–Whitney-U-Test.
  2. CAD coronary artery disease, PAD peripheral artery disease, MI myocardial infarction, HF systolic heart failure (Left ventricular ejection fraction < 55%).
  3. Significant values are in bold italic.