Fig. 1

NBT/MTT ratio in THP-1 cells after 72 h and 96 h of exposure to BJe. Cells were treated with BJe (0.5, 1 and 2.5 mg/mL) for 72 and 96 h. Cell differentiation was assessed by NBT test, whereas viability by MTT test. Results are expressed as mean ± SEM of the ratio between NBT and MTT reduction, and compared to untreated cells (control, CTRL). Three different experiments were carried out by testing each concentration eight-fold (N = 24). **p < 0.01, ***p < 0.001 and ****p < 0.0001 versus CTRL.