Fig. 5 | Scientific Reports

Fig. 5

From: Impact of KDM6B mosaic brain knockout on synaptic function and behavior

Fig. 5

KDM6B mKO animals display cognitive deficits. (A) Quantification of the total distance travelled in the Barnes maze apparatus. (B) Primary latency of Control and KDM6B mKO animals in the Barnes maze apparatus. (C) Quantification of the time spent in the zone of interest where the escape hole was formerly located. (D) Percentage of time spent freezing by Control and KDM6B mKO animals in the contextual fear conditioning test. Bars represents mean ± SEM. Students t-test was used to determine significance compared to control condition. *p < 0.05, **p < 0.01, ***p < 0.001, n = 9 animals for Control and KDM6B mKO animals.

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