Table 1 Study characteristics. Data are expressed as means ± standard deviation (SD).

From: G-quadruplex forming regions in GCK and TM6SF2 are targets for differential DNA methylation in metabolic disease and hepatocellular carcinoma patients

 

Lean-healthy (LH)

Obese-healthy (OH)

Lean-MAFLD (LM)

Obese-MAFLD (OM)

Advanced MetD (aMetD)

n = 24

n = 31

n = 27

n = 32

n = 34

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Gender [f/m]

14/10 (58% f)

21/10 (68% f)

12/15 (44% f)

10/22 (31% f)

15/19 (44% f)

Age [y]

52

8

53

6

54

4

57

3

63

8

BMI [kg/m2]

21.9

2.0

33.1

3.1

23.5

1.3

33.4

3.4

30.1

3.9

HbA1c [%]

5.3

0.2

5.5

0.3

5.4

0.3

5.8

0.5

7.3

1.4

HOMA

1.4

0.5

2.4

1.1

1.6

0.6

4.9

3.2

11.0

15.3

FIB4

1.2

0.4

0.9

0.2

1.1

0.2

1.1

0.3

3.0

1.6

Fast. Glucose [mg/dL]

89.6

7.0

93.5

6.9

91.3

6.3

105.3

16.1

166.0

54.2

Fast. Glucose [mmol/L]

5.0

0.4

5.2

0.4

5.1

0.3

5.8

0.9

9.2

3.0

Fast. Insulin [mU/L]

6.2

2.4

10.5

4.6

7.2

2.8

18.4

9.3

29.3

47.8

GGT [U/L]

15.6

6.5

22.3

12.1

28.3

20.5

55.5

71.6

210.1

219.6

AST [U/L]

20.4

5.5

22.0

5.5

23.7

5.6

29.3

12.7

60.2

41.7

ALT [U/L]

18.8

6.9

24.2

10.1

22.8

9.1

39.9

26.1

76.4

48.0

HDL-c [mg/dL]

69.8

15.0

63.9

19.3

62.7

16.5

52.1

15.8

48.6

13.7

LDL-c [mg/dL]

149.6

32.5

144.0

35.1

152.9

27.8

157.6

44.1

120.7

45.8

TG [mg/dL]

83.6

21.7

92.9

27.7

121.4

62.6

178.3

139.8

198.9

98.7

TChol [mg/dL]

216.8

38.8

211.0

35.6

221.3

28.7

222.3

45.2

195.2

50.5

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