Fig. 1 | Scientific Reports

Fig. 1

From: Methicillin resistant Staphylococcus aureus mazEF expression promotes infections by influencing cellular growth, antibiotic sensitivity, and formation of biofilms

Fig. 1

MRSA lacking mazEF expression displays sensitivity to cefazolin and increased growth of planktonic cells and mature biofilms. Biofilms of each strain were treated with 10×MIC of cefazolin and vancomycin for 24 h in MHB (A) or FBS (B) and percent survival compared to untreated controls was performed. mazF::tn displayed increased susceptibility to cefazolin and vancomycin in both media conditions compared to WT and complement strains. Colony forming unit analysis displayed mazF::tn grew significantly more biofilms on implant material compared to WT and mazF::tn + complement in both MHB and FBS (*p < 0.05) (C).

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