Fig. 4 | Scientific Reports

Fig. 4

From: PIP-seq identifies novel heterogeneous lung innate lymphocyte population activation after combustion product exposure

Fig. 4

Gene co-expression network analysis reveals metabolic changes and upregulation of activation signaling in ILC subsets after exposure to Alt plus BPC. The co-expression network modules were generated using hdWGCNA (A) The top 10 hub genes with the kME plots are shown with the most relevant biological pathways. The modules underwent pathway enrichment analysis using WikiPathways database. (B) The top 2 potential pathways for each pathway subgroup (M1–M9) are shown. (C) Odds ratio (statistic to quantify the association between the gene list in the current module and the gene list for the current Term) between NK/ILC1, and (D) ILC2 between Alt and Alt plus BPC.

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