Fig. 1 | Scientific Reports

Fig. 1

From: CD71 expressing circulating neutrophils serve as a novel prognostic biomarker for metastatic spread and reduced outcome in pancreatic ductal adenocarcinoma patients

Fig. 1

PDAC patients showed increased expression of CD71 on neutrophils. Gating strategy to characterize circulating neutrophils (A); percentage of circulating neutrophils in clinical control (n = 21) and PDAC patients (n = 70) (B); histogram and bar plot denoting the expression of CD71 on circulating neutrophils in clinical control and PDAC patients (C); expression of CD71 on circulating neutrophils in PDAC patients correlated to the pT category (pT), pN category (pN), Grading, perineural invasion (Pn), Venous invasion (V), lymphatic invasion (L) and distant metastasis (M) (D); MFI of CD71 on neutrophils (350 identified by minimal p-value approach) defining the risk for metastasized PDAC (E); survival analysis for PDAC patients with high (≥ 350) and low (< 350) CD71 expression on circulating neutrophils (F); *p < 0.05; **p < 0.01.

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