Table 1 Simulation of single molecule diffusion in curved membranes using different model time-step values, Δt with diffusion coefficient, D = 0.1 µm2⋅s−1 and mock video frame rate = 50fps.
From: Single molecule dynamics in a virtual cell combining a 3-dimensional matrix model with random walks
Rounded cell (8 × 4 × 4 µm3, R = 2 µm) | Rectangular cell (8 × 4 × 4 µm3) | |||
|---|---|---|---|---|
Δt | mean Δx, Δy, Δz | 0.1 ms | 7.7 nm | 1 ms | 24.5 nm | 10 ms | 77.5 nm | 10 ms | 77.5 nm |
Estimated D (µm2⋅s-1) From known x,y,z-trajectories | 0.091 | 0.074 | 0.046 | 0.094 |
Estimated D (µm2⋅s-1) Tracking of mock video movies | 0.093 | 0.071 | 0.056 | 0.094 |