Table 1 Simulation of single molecule diffusion in curved membranes using different model time-step values, Δt with diffusion coefficient, D = 0.1 µm2s−1 and mock video frame rate = 50fps.

From: Single molecule dynamics in a virtual cell combining a 3-dimensional matrix model with random walks

 

Rounded cell (8 × 4 × 4 µm3, R = 2 µm)

Rectangular cell (8 × 4 × 4 µm3)

Δt | mean Δx, Δy, Δz

0.1 ms | 7.7 nm

1 ms | 24.5 nm

10 ms | 77.5 nm

10 ms | 77.5 nm

Estimated D (µm2s-1)

From known x,y,z-trajectories

0.091

0.074

0.046

0.094

Estimated D (µm2s-1)

Tracking of mock video movies

0.093

0.071

0.056

0.094