Table 2 Cytokine release assays for PBMCs and primed and non-primed NK cells.

From: Phase I study of safety and efficacy of allogeneic natural killer cell therapy in relapsed/refractory neuroblastomas post autologous hematopoietic stem cell transplantation

Composition

Cytokine release (ng/mL)

IFN-γ

TNF-α

PBMCs

0.7

0.1

Naïve NK cells

1

0.2

IL-2-activated NK

3.2

0.8

IL-2- and IL-15-activated NK cells

6

1.4

  1. IL interleukin; IFN-γ interferon-gamma; mL milliliters; ng nanograms; NK natural killer; PBMC peripheral blood mononuclear cell; TNF-α tumor necrosis factor-alpha.
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