Fig. 5
From: SARS-CoV-2 envelope protein alters calcium signaling via SERCA interactions

E protein binds to SERCA similarly to PLN. (a) PLN (burgundy) in the model of the human SERCA/PLN complex and (b) E protein (blue) from PIPER/ClusPro docking. SERCA is colored yellow-green-turquoise. The interaction frequency (white to blue) of (c) PLN and (d) E protein calculated from simulations are projected to SERCA TM helices.