Fig. 4 | Scientific Reports

Fig. 4

From: Preclinical modeling of metabolic syndrome to study the pleiotropic effects of novel antidiabetic therapy independent of obesity

Fig. 4

Serum insulin time-course post-glucose tolerance test. Dogs received an oral dose of 5 g of dextrose per kg in the form of a solution containing 1 g of dextrose powder per mL of water. Blood samples were collected at 30, 60, 90, 120, and 180 min after oral administration of the glucose solution. Compared to BAS1, dogs fed an isocaloric WD for ten weeks showed a trend towards a higher peak concentration of insulin, with an increase of approximately 35% in AUCins(0–90) at BAS2. Time-course data are presented as mean ± S.E. Scatter plots produced using the ggplot2 package in R version 4.2.2.

Back to article page