Fig. 7
Temporal changes in antioxidant (A) and oxidant (B) stress markers after ten weeks of feeding with a high-fat, high-monosaccharide, low-fiber western diet. The WD had mild effects on antioxidant markers, with no significant changes in CUPRAC, FRAP, TEAC, and Thiol values. However, PON-1 levels significantly decreased at BAS2. The impact of the WD on oxidative stress parameters was more consistent, with total oxidant status significantly increasing at BAS2. The increase extended to reactive oxygen metabolites (d-ROMs). Conversely, there was a decrease in POX-Act post-WD, but no notable effects on AOPP. Box plots represent the 25th, 50th and 75th percentile of the data ± 1.5 IQR (interquartile range). •: 0.01 < P ≤ 0.05; ••: 0.001 < P ≤ 0.01; •••: P ≤ 0.001. Summary box plots produced using the ggplot2 package in R version 4.2.2.
