Fig. 7
From: The molecular basis of the anticancer effect of statins
Simvastatin and Lovastatin, selected from our data-driven analysis and substantiated by retrospective meta-analyses and extensive current prescriptions data, have demonstrated their antitumor activity rooted in Synthetic Lethality through experimental validation. This compelling evidence irrefutably establishes its therapeutic principle of statins, marking a significant stride in the realm of personalized medicine based on data-driven repurposed drugs.
