Table 1 Characteristics of PrEC and derived clones.
CDKN2A locus | Exp. Markers (western blot) | Surface Markers | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Exon1β | Exon1α | Exon 2 | hTERT | p16 | p14 | AR | p63 | CK5 | CK8 | Normal pRB/p53 signaling | CD326 | CD26 | CD271 | |
PrEC | WT | WT | WT | – | + | nd | – | + | + | Low | + | > 99% | > 4% | > 99 |
Cl-1 | WT | WT | Δ (+ 1) | + | – | – | – | + | + | – | + | > 78% | > 4.7 | > 23 |
Cl-2 | NP* | NP* | NP* | + | – | – | – | + | + | Low | + | > 80% | > 3.4 | > 70 |
Cl-3 | WT | WT | NP* | + | – | – | – | + | + | Low | + | > 90% | > 5.6 | > 58 |
p16-KO | WT | Δ (− 11) Δ (− 74) | WT | + | – | low | – | + | + | Low | + | > 73% | > 2.6 | > 64 |
