Fig. 5
From: Microglial process convergence onto injured axonal swellings, a human postmortem brain tissue study
Injured axons have higher Iba-1 + microglia fluorescent intensity than MBP + intact myelinated fibers. Box and whisker plots depicting the integrated density of Iba-1 + microglia within axonal segments of MBP + intact axonal fibers in either control cases (n = 161 fibers) or DAI cases (n = 36 fibers) and APP + injured axonal swellings in control cases (n = 105 swellings) or DAI cases (n = 173 swellings). Injured APP + axonal swellings in either control or DAI tissue had significantly higher Iba-1 + fluorescent intensity within the swellings compared to intact MBP + axonal fibers. *p < 0.05.
