Table 2 Mutations of Ts/Tv on HA and NA genes during two stages.

From: The evolutionary features and roles of single nucleotide variants and charged amino acid mutations in influenza outbreaks during NPI period

Itema

HA mutation

NA mutation

Before NPI

After NPI

Assessmentd

Before NPI

After NPI

Assessment

Nob

Ratioc

No

Ratio

No

Ratio

No

Ratio

(%)

(%)

(%)

(%)

Ts/A → G

168

6.72

343

7.3

–

160

6.4

305

6.49

–

Tv/A → C

0

0

0

0

–

25

1

50

1.06

–

Tv/A → T

25

1

48

1.02

–

24

0.96

90

1.91

↑

Ts/C → T

134

5.36

370

7.87

↑

144

5.76

171

3.64

–

Tv/C → A

4

0.16

103

2.19

↑↑

0

0

2

0.04

–

Tv/C → G

0

0

1

0.02

–

0

0

0

0

–

Ts/G → A

153

6.12

457

9.72

↑

57

2.28

226

4.81

↑

Tv/G → C

0

0

0

0

–

0

0

0

0

–

Tv/G → T

24

0.96

48

1.02

–

0

0

0

0

–

Ts/T → C

251

10.04

370

7.87

↓

35

1.4

70

1.49

–

Tv/T → A

1

0.04

34

0.72

↑↑

49

1.96

48

1.02

↓

Tv/T → G

0

0

0

0

–

25

1

48

1.02

–

  1. aThe reference of mutation was Bri/60/08; bThe number of mutation sites; cThe ratio of the number of site mutations to all site/strain number, where the number before NPI was 25 and that after NPI was 47; dthe assessment was based on an increase or decrease of the ratio of the number of mutation sites to 25% (↑/↓) and an increase or decrease of the ratio to 50% (↑↑/↓↓).
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