Table 2 Laboratorial parameters of healthy donors and convalescent patients at D30, D60 and D90.

From: Immunologic mediators profile in COVID-19 convalescence

Variables

HD

n = 51

D30

n = 62

D60

n = 48

D90

n = 47

p value

RBC (× 106/µL, median [IQR])

4.99 [4.59–5.40]

4.90 [4.56–5.20]

4.89 [4.47–5.15]

4.89 [4.71–5.29]

0.4676

Hemoglobin (g/dL, median [IQR])

14.90 [13.60–16.00]

14.40 [13.38–15.03]

14.35 [13.23–14.90]

14.40 [13.50–15.10]

0.0602

Hematocrit (%, median [IQR])

44.70 [40.6–47.4]

42.60 [40.45–45.45]

42.75 [39.13–44.50]

43.90 [41.50–46.20]

0.0660

MCV (fL, median [IQR])

87.80 [84.70–90.40]

88.15 [84.85–90.80]

87.90 [84.35–91.08]

89.10 [85.30–91.40]

0.7292

MCH (pg, median [IQR])

29.70 [28.8–30.70]

29.60 [28.38–30.60]

29.85 [28.10–30.70]

29.80 [27.90–30.80]

0.8607

MCHC (g/dL, median [IQR])

34.05 [33.10–34.60]

33.70 [32.78–34.450]

33.59 [32.75–34.48]

33.40 [32.60–34.10]

0.1667

RDW (%, median [IQR])

13.70 [13.10–14.00]

14.40 [13.75–14.95]

14.40 [13.90–15.08]

14.35 [13.68–15.03]

< 0.0001a,b,c

WBC (× 106/µL, median [IQR])

6.33 [5.17–6.95]

6.78 [5.87–7.51]

6.34 [5.75–7.57]

6.65 [5.61–7.97]

0.2906

Neutrophil (× 103/µL, median [IQR])

3.34 [2.8–4.17]

4.00 [3.21–4.65]

3.80 [3.14–4.61]

3.79 [3.04–4.84]

0.0757

Lymphocyte (× 103/µL, median [IQR])

1.85 [1.59–2.18]

1.98 [1.61–2.22]

1.93 [1.6–2.3]

1.98 [1.61–2.23]

0.8081

Monocyte (× 103/µL, median [IQR])

0.38 [0.28–0.42]

0.43 [0.37–0.48]

0.37 [0.33–0.42]

0.38 [0.28–0.43]

0.0028a,d,e

Basophil (× 103/µL, median [IQR])

0.03 [0.02–0.05]

0.04 [0.02–0.06]

0.03 [0.02–0.04]

0.03 [0.02–0.05]

0.2906

Eosinophil (× 103/µL, median [IQR])

0.19 [0.12–0.38]

0.19 [0.13–0.26]

0.18 [0.13–0.26]

0.16 [0.12–0.26]

0.6799

Platelet count (× 103/µL, median [IQR])

243.0 [210–282]

259.5 [212–290]

245.0 [215–266]

245.00 [209–272]

0.7717

  1. aSignificant difference for HD vs D30; bSignificant difference for HD vs D60; cSignificant difference for HD vs D90; dSignificant difference for D30 vs D60; eSignificant difference for D30 vs D90; fSignificant difference for D60 vs D90. Statistical analysis was performed with Kruskal–Wallis test, and Dunn’s Multiple Comparison Test to compare hematological values from all groups. A p < 0.05 was considered significant and highlighted by bold type font.
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