Fig. 7 | Scientific Reports

Fig. 7

From: Third-party punishment-like behavior in a rat model

Fig. 7

EAH-induced changes in gene expression in the mPFC. (a) Significant results from comparison of the gene expression in the medial prefrontal cortex (mPFC) between CNT and EAH rats were obtained by RNAseq; Rps20_3, Fos, Egr1, and Ier2. (b, c) Increased Rps20 (b) and Fos (c) expression in EAH brains as revealed by qPCR. (d) Gene expression encoding oxytocin (Oxt) in the hypothalamus did not significantly change. (e, f) Rps20 protein expression was found in neurons (e, CNT; f, EAH brains) (green; Rps20, white; a neuronal marker NeuN, red; a microglia marker CD11b). Unpaired two-tailed t-test. *, **, ***, **** indicate statistical significance at p < 0.05, 0.01, 0.001, and 0.0001, respectively.

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