Fig. 10 | Scientific Reports

Fig. 10

From: Multi-modal transcriptomic analysis reveals metabolic dysregulation and immune responses in chronic obstructive pulmonary disease

Fig. 10

Enrichment and proposed time-series analysis of single-cell data. (A) Presents a histogram depicting cell type proportions across each single-cell sample. (B) Features a heatmap of gene ontology (GO) enrichment analysis for various cell types. (C) Illustrates the proposed time-series trend for all cells, indicating a temporal progression from black to blue. (D) Outlines the proposed time-series analysis for different cell types, aimed at tracking their temporal changes. (E) and (F) Describe the implementation of monocle2 for a proposed time-series line graph and plot, respectively, of the single-cell data. Lastly, (G) showcases a figure representing the proposed time-series analysis, with a focus on the progression of type II alveolar epithelial cells as the initial point of study.

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