Fig. 12

Analysis and molecular docking of COPD diagnosis-related feature genes. (A) Presents the expression visualization of four COPD diagnosis-related feature genes within single-cell data. (B) (initially labeled as (D)) Proposes a time-series analysis of cell clusters exhibiting significant differences. (C) Depicts a time-series heatmap for these feature genes, illustrating temporal progression from blue to red. (D) Delves into a time-series analysis of these feature genes in notably differentiated cell clusters. (E) Extends this analysis to the expression patterns of these genes in corresponding clusters where they are highly expressed. Finally, (F) explores the molecular docking interactions between NFE2L1 and resveratrol, providing insights into the potential molecular mechanisms underpinning their relationship in the context of COPD. This comprehensive approach combines expression analysis with molecular docking to enhance the understanding of gene roles in COPD diagnosis.