Fig. 2 | Scientific Reports

Fig. 2

From: Multi-modal transcriptomic analysis reveals metabolic dysregulation and immune responses in chronic obstructive pulmonary disease

Fig. 2

This study involved the identification and GSEA enrichment analysis of differential genes between Control and COPD. In (A), a Volcano plot illustrates differential gene expression, with up-regulation indicated by |log2FC|> 0, p < 0.05 and down-regulation by |log2FC|< 0, p < 0.05. Genes were selected based on |log2FC|> 1, p < 0.05 criteria, with blue denoting down-regulation and red signifying up-regulation. (B) Features a heatmap contrasting Control (blue module) with COPD (red module), where red and blue colors correspond to up- and down-regulated expressions, respectively. Finally, (C,D) present GSEA enrichment analyses, highlighting the top five and bottom five enriched pathways.

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