Table 2 The Result of Generalized Linear mixed regression analysis.
From: The biphasic impact of apolipoprotein E ε4 allele on age-related hearing loss
Baseline model (Marginal \({{\varvec{R}}}^{2}\) = 0.17, Conditional \({{\varvec{R}}}^{2}\) = 0.72) | |||
|---|---|---|---|
Fixed Effect (Predictors) | Estimates | Std. Error | P |
Age | 1.802 | 0.181 | < 0.001*** |
ε4 ( +) | -0.389 | 0.212 | 0.003** |
ε4 ( +) * Age | 0.649 | 0.368 | 0.003** |
Random Effect | Variance | Std. Deviation | |
Subjects | 0.169 | 0.131 | |
Frequency | 0.111 | 0.098 | |
Model evaluation | Log-likelihood | RMSE | |
3656.5 | 0.146 | ||
Fully Adjusted model (Marginal \({{\varvec{R}}}^{2}\) = 0.19, Conditional \({{\varvec{R}}}^{2}\) = 0.73) | |||
|---|---|---|---|
Fixed Effect (Predictors) | Estimates | Std. Error | P |
Age | 1.784 | 0.096 | < 0.001*** |
Sex (Male) | 0.136 | 0.026 | < 0.001*** |
Hypertension (yes) | 0.024 | 0.027 | 0.356 |
Diabetes (yes) | 0.092 | 0.028 | 0.001** |
ε4 ( +) | -0.353 | 0.126 | 0.005** |
ε4 ( +) * Age | 0.577 | 0.214 | 0.006** |
Random Effect | Variance | Std. Deviation | |
Subjects | 0.160 | 0.401 | |
Frequency | 0.109 | 0.331 | |
Model evaluation | Log-likelihood | RMSE | |
3838.4 | 0.144 | ||
