Table 3 Summary statistics for the group of patients < 75- and ≥ 75-year-old.

From: The biphasic impact of apolipoprotein E ε4 allele on age-related hearing loss

Parameter

Age < 75

Age ≥ 75

Total (n = 442)

ε4 (+) (n = 113)

ε4 (−) (n = 329)

P

Total (n = 720)

ε4 (+) (n = 167)

ε4 (−) (n = 553)

P

Age (years)

67.13 ± 6.4

67.6 ± 5.4

67.0 ± 6.2

0.326

81.03 ± 4.7

80.2 ± 3.9

81.3 ± 4.4

0.002**

 

Sex

Male

154 (34.8%)

37 (32.7%)

117 (35.6%)

0.669

302 (41.9%)

74 (43.3%)

228 (41.2%)

0.640

Female

288 (65.2%)

76 (67.3%)

212 (64.4%)

 

418 (58.1%)

93 (55.7%)

325 (58.8%)

 

MMSE

25.4 ± 4.6

25.2 ± 4.5

25.5 ± 4.8

0.615

21.12 ± 7.2

20.4 ± 6.1

21.3 ± 6.8

0.119

PTAa (dB HL)

24.4 ± 14.7

21.1 ± 11.1

25.6 ± 14.5

0.001***

29.17 ± 17.63

41.1 ± 16.8

40.0 ± 17.4

0.471

SDS (%)

90.1 ± 12.5

94.9 ± 9.0

88.7 ± 13.8

 < 0.001***

73.23 ± 26.9

75.5 ± 22.4

72.5 ± 26.4

0.305

Diabetes

Normal

339 (75.7%)

90 (77.6%)

249 (75.0%)

0.665

487 (68.2%)

113 (68.9%)

374 (68.0%)

0.903

Abnormal

109 (24.3%)

26 (22.4%)

83 (25.0%)

 

227 (31.8%)

51 (31.1%)

176 (32.0%)

 

Hyper tension

Normal

257 (57.4%)

67 (57.8%)

190 (57.2%)

 > .999

298 (4107%)

68 (41.5%)

230 (41.8%)

 > .999

Abnormal

191 (42.6%)

49 (42.2%)

142 (42.8%)

 

416 (58.3%)

96 (58.5%)

320 (58.2%)

 

Lipid tests

LDL Cholesterol (mmol/L)

93.8 ± 33.5

95.4 ± 31.1

93.4 ± 34.2

0.678

105.8 ± 33.3

108.2 ± 31.3

105.1 ± 34.1

0.547

HDL Cholesterol (mmol/L)

50.8 ± 14.9

50.2 ± 17.3

51.0 ± 14.2

0.725

53.0 ± 14.63

52.9 ± 14.5

53.0 ± 14.7

0.977

Total Cholesterol (mmol/L)

169.0 ± 39.5

168.1 ± 37.7

169.3 ± 40.1

0.678

185.5 ± 39.2

192.2 ± 38.4

183.3 ± 39.4

0.115

Triglyceride (mmol/L)

118.6 ± 80.6

119.7 ± 61.1

118.4 ± 85.8

0.875

123.8 ± 84.9

122.2 ± 71.1

124.4 ± 89.4

0.845

  1. aAverage of 500, 1000, 2000, 4000 Hz frequency thresholds. MMSE, Mini-Mental State Examination; PTA, pure tone audiometry; SDS, speech discrimination score; LDL, low density lipoprotein; HDL, high density lipoprotein.