Fig. 2
From: Variant load of mitochondrial DNA in single human mesenchymal stem cells
Somatic heteroplasmic count and heteroplasmic fraction distributions are similar across all 13 patient samples. Boxplots and strip charts showing the count of somatic heteroplasmies per cell per sample (upper) and the heteroplasmic fraction (lower, HF > 0.02/< 0.98) of each somatic heteroplasmic variant detected in each single-MSC grouped by sample. We observed no significant difference in heteroplasmy counts or heteroplasmy fraction distribution between samples (for each, ANOVA p > 0.05 and Dunnett’s p > 0.05 with patient 1 as reference). Boxes denoted 25th and 75th percentile, whiskers indicate 95th percentile and the horizontal line indicates the median.
