Table 3 Subgroup analysis of the associations between NLR and cardiovascular mortality among cancer participants.

From: Neutrophil-to-lymphocyte ratio as a predictor of cardiovascular mortality in cancer survivors

Subgroups

Participants N

Events N

HR

95% CI

P value

P value for interaction

Age, year

0.346

 < 70

  Lower NLR

1748

32

Ref

   

  Higher NLR

727

29

1.53

0.81–2.88

0.184

 

 > 70

  Lower NLR

1390

150

Ref

   

  Higher NLR

1109

190

1.79

1.37–2.32

 < 0.001

 

Gender

0.241

 Male

  Lower NLR

1316

93

Ref

   

  Higher NLR

1023

153

1.98

1.40–2.81

 < 0.001

 

 Female

  Lower NLR

1822

89

Ref

   

  Higher NLR

813

66

1.27

0.87–1.87

0.211

 

 Smoke

0.252

 Ever

  Lower NLR

1671

102

Ref

   

  Higher NLR

1081

135

1.66

1.19–2.32

0.002

 

 Never

  Lower NLR

1467

80

Ref

   

  Higher NLR

755

84

1.49

0.97–2.28

0.064

 

HBP

0.849

 Yes

  Lower NLR

1688

122

Ref

   

  Higher NLR

1109

165

1.73

1.29–2.33

 < 0.001

 

 No

  Lower NLR

1450

60

Ref

   

  Higher NLR

727

54

1.43

0.95–2.16

0.081

 
  1. Survey sample weights were taken into consideration in the Cox models accompanying the NHANES data. Multivariate Cox analysis was adjusted for gender, age, race, marital status, educational level, family income level, smoke history and the presence of comorbidities such as DM, CHD, HF, HBP, high cholesterol, stroke, chronic bronchitis and liver diseases.
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