Fig. 1

Analysis of tumor and brain stiffness. The KruskalāWallis test was used to compare stiffness between the normal brain (blue box, nā=ā25) and the SF126-firefly luciferase-mCherry (FmC) (red box, nā=ā5), U87-FmC (red box, nā=ā5), U251-FmC (red box, nā=ā5), IOMM-Lee-FmC (green box, nā=ā5), and HKBMM-FmC (green box, nā=ā5) tumors if there were statistically significant overall differences (upper panel). The KruskalāWallis test was performed to compare the stiffness of the normal brain (nā=ā25), the three types of glioblastoma (SF126-FmC [red box, nā=ā5], U87-FmC [red box, nā=ā5], and U251-FmC [red box, nā=ā5]; i.e. nā=ā15 in total), and the two types of malignant meningioma (IOMM-Lee-FmC [green box, nā=ā5] and HKBMM-FmC [green box, nā=ā5]) if there were statistically significant differences between the normal brain, glioblastoma, and malignant meningioma tissues (lower panel).