Fig. 3

MetaCore™ pathway analysis of prevalently expressed miRNA differentiating decompensated cirrhosis states from cCLD and HC. (A) Network of gene and miRNA expression from MetaCore™ pathway analysis of miRNA which discriminated between compensated and decompensated states. Thick cyan lines indicate fragments of canonical pathways. Up-regulated genes are marked with red circles. Down-regulated genes are marked with blue circles. ‘Checkerboard’ color indicates mixed expression for the gene between files or between multiple tags of the same gene. (B) Processes associated with miRNA from this signature.