Fig. 5

Model discriminating patients with decompensated cirrhosis from those without. (A) Original model (n = 174,AUC 0.77 (95% CI 0.69–0.85, p < 0.0001*). (B) Excluding patients with dCLD (n = 80, AUC 0.76 (95% CI 0.65–0.86, p < 0.0001*). (C) Excluding patients with ACLF and AD (n = 134, AUC 0.78 (95% CI 0.69–0.86, p < 0.0001*). (D) Excluding healthy controls (n = 154, AUC 0.69 (95% CI 0.56–0.81, p = 0.008*). (E) Excluding HC and the 6 cCLD patients who decompensated the year after sampling (n = 148, AUC 0.74 (95% CI 0.60–0.88, p < 0.0001*). (F) Excluding the 6 cCLD patients who decompensated the year after sampling (n = 168, AUC 0.81 (95% CI 0.73–0.89, p < 0.0001*). Statistical significance set after correction for false discovery with the Benjamini–Hochberg procedure (p < 0.0344) and designated by *.