Fig. 2 | Scientific Reports

Fig. 2

From: Screening of the Pandemic Response Box library identified promising compound candidate drug combinations against extensively drug-resistant Acinetobacter baumannii

Fig. 2

Antibacterial activities against A. baumannii QS17-1084 in the Pandemic Response Box collection at 10 µM concentration. Activities of known antibacterials are represented by blue circles [colistin (12.6 µM), erythromycin (12.8 µM), doxycycline (8.3 µM), imipenem (12.6 µM), and ciprofloxacin (9.4 µM)]. Most of the compounds had activities below the 50% growth inhibition cutoff. Seven of the most active compounds were selected for further tests based on their ability to inhibit the growth of A. bamannii QS17-1084 in the 80–100% range. These compounds are indicated by red circles.

Back to article page