Table 1 Information on the compounds selected from the MMV Pandemic Response Box collectiona.
MMV-ID (Trivial name) | Structureb | Original reported activity | Growth inhibition at 10 μM (%) (mean ± SD) (n = 3) | |
|---|---|---|---|---|
A. baumannii | ||||
QS17-1084 | 5075 | |||
MMV396785 (Alexidine) |
| Antifungal | 100 ± 0.0 | 100 ± 0.0 |
MMV1578568 (Gepotidacin) |
| Antibacterial | 80.5 ± 1.5 | 95.3 ± 3.5 |
MMV1580854 |
| Antibacterial | 96.8 ± 2.5 | 97.7 ± 1.9 |
MMV1578574 (Eravacycline) |
| Antibacterial | 99.5 ± 0.4 | 100 ± 0.0 |
MMV1578566 (Epetraborole) |
| Antibacterial | 93.8 ± 4.2 | 100 ± 0.0 |
MMV1634402 (Brilacidin) |
| Antibacterial | 99.5 ± 0.4 | 100 ± 0.0 |
MMV1578564 (MUT056399) |
| Antibacterial | 86.8 ± 2.9 | 95.4 ± 3.4 |
