Table 2 Inhibitory and bactericidal properties of the selected MMV Pandemic response box compounds and control drugs.
Compound | Antibacterial activity (MICs and MBCs [μM]a | |||
|---|---|---|---|---|
A. baumannii QS17-1084 | A. baumannii 5075 | |||
MIC | MBC | MIC | MBC | |
Alexidine | 10 | 10 | 5 | 5 |
Gepotidacin | 40 | 40 | 40 | 40 |
MMV1580854 | > 160 | > 160 | > 160 | > 160 |
Eravacycline | 20 | 20 | 1.25 | 1.25 |
Epetraborole | 20 | > 80 | 5 | > 80 |
Brilacidin | 10 | 10 | 10 | 10 |
MUT056399 | > 160 | > 160 | > 160 | > 160 |
Doxycycline | 133 | 133 | 1 | 1 |
Imipenem | 50 | 50 | 50 | 100 |
