Fig. 1

(a) Frequency of IgM and IgG antibodies responders. Bars indicate the percentage of IgM responders (light gray bar), IgG responders (dark gray bar), and both combined (black bar). **** = p < 0.0001. (b) Reactivity of IgM and IgG antibodies. RI’s of the entire population for both IgM and IgG are demonstrated in this graph. The red dotted line separates responders from non-responders, values of RI’s above 1 are considered IgM (light gray) and/or IgG (dark gray) responders. (p < 0.0001 = ****). (c) Frequency of IgM responders per group. Bars indicate the percentage of IgM responders in each group: P. vivax (pink bar), cohabitants (blue bar) and exposed (orange bar). P values are 0.0015 for ** and 0.0004 for ***. (d) Reactivity of IgM antibodies per group. RI’s of each group for IgM antibodies against PvCyRPA is demonstrated in this graph. P vivax group is represented with a pink bottle, the cohabitants group with a blue bottle, and the exposed one with an orange bottle. P values are 0.0010 for *** - P. vivax x exposed and 0.0001 for *** - P. vivax x cohabitants. (e) Frequency of IgG responders per group. Bars indicate the percentage of IgG responders to in each group: P. vivax (pink bar), cohabitants (blue bar) and exposed (orange bar). (f) Reactivity of IgG antibodies per group. RI’s of each group for IgM antibodies against PvCyRPA is demonstrated in this graph. P vivax group is represented with a pink bottle, the cohabitants group with a blue bottle, and the exposed one with an orange bottle. The red dotted line separates responders from non-responders, values of RI’s above 1 are considered responders. RI’s analyzes were done by Kruskal-Wallis test and Dunn’s multiple comparison test, while frequencies were compared through Fisher’s exact test.