Fig. 4 | Scientific Reports

Fig. 4

From: Characterization of T and B cell epitopes in PvCyRPA by studying the naturally acquired immune response in Brazilian Amazon communities

Fig. 4

(a) Frequency of IgG responders to different PvCyRPA B cell epitopes. The percentage of IgG antibody responders to each one of the 7 predicted; (b) Reactivity of IgG antibodies against PvCyRPA B cell epitopes. RI’s of 51 individuals that respond with IgG antibodies are demonstrated in this graph for each of the 7 predicted B cell epitopes. The red dotted line separates responders from non-responders, values of RI’s above 1 are considered responders to each one of the B cell epitopes. B1 x B2 (p = 0.0084**), B1 x B3 (p < 0.0001****), B1 x B6 (0.0004***), B7 x B2 (p = 0.0248*), B7 x B3 (p = 0.0001***), B7 x B6 (p = 0.0115) and B4 x B3 (p = 0.0115*). RI’s analyzes were done by Kruskal-Wallis test and Dunn’s multiple comparison test, while frequencies were compared through Fisher’s exact test.

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