Fig. 5

Effects of LF on gut microbial composition of depressed rats. (a) Composition at the phylum level. The ratio of Firmicutes and Bacteroidetes (F/B) increased in L group relative to M group. (b) t-test analysis at the phylum level. (c) t-test analysis at the family level (d) t-test analysis at the genus level. (e) Histogram of LDA analysis. When species with LDA Score > 4 are statistically different, the length of the histogram (LDA Score) represents the impact size of the different species. (f) The distribution difference of flora was analyzed using LEfSe. Note: Compared to group K, *p < 0.05, **p < 0.01; and compared to group M, #p < 0.05, ##p < 0.01. K control group; M model group; L LF treatment group.