Fig. 2 | Scientific Reports

Fig. 2

From: CD8 + T-cells restrict the development of peritoneal metastasis and support the efficacy of hyperthermic intraperitoneal chemotherapy (HIPEC)

Fig. 2

Impact of HIPEC treatment in PM mouse model. (a) measurement of peritoneal tumor load as PCI. mice were treated with PBS ( n = 9) or heated PBS ( n = 7) or with M/D (n = 10) or with heated M/D (n = 11). (b) Staining of tumor tissues for the presence of CD8 + T cells, Granzyme B + cells and macrophages. (c and d) Quantification of CD8 + T cells and GZMB + cells. (e) PCI of the treated mice with and without CD8 + T-cells. Each dot represents one mouse. Error bars show the mean +/-SD. **** = p ≤ 0.0001, *** = p ≤ 0.001, ** = = p ≤ 0.01,* = p ≤ 0.05, ns = p > 0.05.

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