Fig. 10 | Scientific Reports

Fig. 10

From: Leveraging cell death patterns to predict metastasis in prostate adenocarcinoma and targeting PTGDS for tumor suppression

Fig. 10

Molecular features of PTGDS at the single-cell level. (A) t-SNE of 8 cell types; (B) t-SNE of metastasis and no-metastasis patients; (C) t-SNE of the distribution of PTGDS among different types; (D) The differentially expressed genes among the identified 8 cell types; (E) Gene set variation analysis of PRAD cells with different levels of PTGDS; (F) Pseudotime trajectory analysis based on PTGDS expression; (G) The quantity of interactions in a network of cell-cell communication; (H) The weights and strengths of the cell-to-cell communication network interactions; (I–K) Cellular interaction networks between PRAD cells with different PTGDS level and other cells in MK(I), MIF(J), and VISFATIN signaling pathway(K).

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