Fig. 5 | Scientific Reports

Fig. 5

From: Sex-specific proximal tubular cell differentiation pathways identified by single-nucleus RNA sequencing

Fig. 5

Velocity and pseudotime analysis. (A) Velocity analysis shows that PTCs differentiation starts from proliferative PTCs and goes toward S1 and S3. (B) Result of pseudotime analysis. (C) Gene expression along pseudotime of marker genes of the PTC clusters. (D) Expression of genes selected from the DEG analysis, plotted along pseudotime in female and male mouse kidneys. Xist, Uty, Ddx3y and Kdm5d were persistently expressed throughout PTC differentiation whereas other genes demonstrate restricted expression patterns.

Back to article page