Fig. 3
From: Vitamin D3 reduces the expression of M1 and M2 macrophage markers in breast cancer patients
Correlations of vitamin D3 (VD)-related factors with the expression of selected proteins in tumor tissue. Spearman correlation coefficients for (A) 25(OH)D3 [ng/mL], (B) VDR, and (C) CYP24A1. The numbers of patients were as follows: (A) VD-normal, IRF4, N = 23; ZEB1, N = 20; premenopausal, IRF4, N = 28; lymph node metastatic (LN-metastatic), CYP24A1, N = 27; (B) VD-normal, ZEB1, N = 20; VD-deficient, CYP24A1, N = 57; premenopausal, ZEB1, N = 26; LN-metastatic, CYP24A1, N = 27; and (C) postmenopausal, EpCAM, N = 51; and LN-metastatic, EpCAM and OPN, N = 27. IRF4, interferon-regulatory factor 4; ZEB1, proteins from the E-Box zinc finger family binding homeobox 1; CYP24A1, 24-hydroxylase; VDR, vitamin D receptor; EpCAM, epithelial cell adhesion molecule antigen; OPN, osteopontin; *P < 0.05, **P < 0.01.
