Fig. 4
From: Vitamin D3 reduces the expression of M1 and M2 macrophage markers in breast cancer patients
CYP27B1 correlations with tumor tissue proteins. Spearman r correlations of CYP27B1 with (A) TGFβ: all patients N = 64, VD-normal N = 16, premenopausal N = 24, postmenopausal N = 40, nonmetastatic N = 39, LN-metastatic N = 21; (B) OPN: all patients N = 79, VD-normal N = 22, VD-deficient N = 57, premenopausal N = 28, postmenopausal N = 51, nonmetastatic N = 48, LN-metastatic N = 27; (C) IRF4: postmenopausal N = 40; (D) EpCAM: nonmetastatic N = 48, LN-metastatic N = 27. TGFβ, transforming growth factor β; OPN, osteopontin; IRF4, interferon-regulatory factor 4; EpCAM, epithelial cell adhesion molecule antigen; CYP27B1, 1α-hydroxylase; VD, vitamin D3; *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.
