Table 2 Clinical characteristics of patients stratified according to metastasis* and HER2 status.

From: Vitamin D3 reduces the expression of M1 and M2 macrophage markers in breast cancer patients

Parameter

Nonmetastatic (N0M0)

LN-metastatic (N + M0)

P

Distant-metastatic (M1)

P vs. N0M0

P vs. N + M0

HER2

HER2+

P

Age

N

88

32

 

11

  

39

81

 
 

(years)

59.5 (31–85)

60 (36–83)

> 0.999

66 (38–75)

0.959

> 0.999

57 (44–83)

63 (31–85)

0.516

BMI

N

84

31

 

11

  

38

76

 
 

(kg/m2)

26.8 (16.5–42.5)

26.8 (20.0–39.5)

> 0.999

25.4 (19.6–28.7)

> 0.999

0.605

27.9 (16.5–40.4)

26.6 (17.2–42.5)

0.202

25(OH)D3

N

88

32

 

10

  

39

81

 
 

(ng/mL)

23.3 (2–67.7)

23.6 (7.14–60.1)

> 0.999

26.3 (9.7–39.6)

> 0.999

> 0.999

21.5 (7.14–67.7)

23.7 (2–60.1)

0.868

FSH

N

88

31

 

9

  

39

80

 
 

(mIU/mL)

60.8 (2.4–154)

54.8 (6.2–105)

> 0.999

59.8 (2.1–96.9)

> 0.999

> 0.999

65 (3.3–112)

56.4 (2.4–154)

0.348

Estradiol

N

88

32

 

10

  

39

81

 
 

(pg/mL)

14 (4–574)

16.5 (4–617)

> 0.999

11 (4–135)

> 0.999

> 0.999

14 (4–390)

13 (4–617)

0.882

PTH

N

88

32

 

7

  

39

81

 
 

(pg/mL)

29.9 (18–230)

31.2 (18.5–57.4)

> 0.999

38.6 (4.6–48.2)

> 0.999

> 0.999

34.2 (18.5–91.3)

29.6 (18–79.4)

0.090

  1. Statistical analysis: Dunn’s multiple comparison tests; *according to TNM classification: N, sentinel lymph node (LN) spread; M, distant metastases.