Fig. 2 | Scientific Reports

Fig. 2

From: Photoperiod effects on corticosterone and seasonal clocks in cafeteria-induced obese fischer 344 rats are influenced by gut microbiota

Fig. 2

Corticosterone serum levels and GR expression in pituitary gland and colon. (a) Corticosterone serum levels in STD, CAF and CAF treated with ABX rats housed under three different photoperiods (L6, L12 and L18). (b) Relative GR expression (Nr3c1) in pituitary gland; (c) Relative gene expression of the GR (Nr3c1) in colon tissue; Data were analyzed by two-way ANOVA followed by pairwise comparison Sidak post hoc test: *indicates CAF effect (*p < 0.05; **p ≤ 0.01), #indicates ABX effect (#p < 0.05) and ab letters indicate photoperiod effect in each experimental group; Data are plotted as the mean ± SEM (n = 7–8). L6: 6 h light/18 h darkness, L12: 12 h light/12 h darkness, L18: 18 h light/6 h darkness, STD: standard chow diet, CAF: cafeteria diet, ABX: antibiotic cocktail (0.5 g/l ampicillin, 0.250 g/l vancomycin and 0.125 g/l imipenem). Nr3c1: nuclear receptor subfamily 3, group C, member 1.

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