Fig. 6 | Scientific Reports

Fig. 6

From: Photoperiod effects on corticosterone and seasonal clocks in cafeteria-induced obese fischer 344 rats are influenced by gut microbiota

Fig. 6

Experimental design. 13-week-old male F344 rats were pair-housed under three different photoperiods (6, 12 or 18 h of light per day) for 9 weeks. In each photoperiod, rats were fed a STD or CAF diet. During the last 4 weeks, a group of CAF-fed rats were treated with an antibiotic cocktail (ABX) in drinking water (ampicillin: 0.5 g/l, vancomycin: 0.25 g/l, imipenem: 0.125 g/l). All rats were sacrificed at the same time point (3 h after the light was turned on, i.e., ZT3). F344: fischer 344 rats, OGTT: oral glucose tolerance test, L6: 6 h light/18 h darkness, L12: 12 h light/12 h darkness, L18: 18 h light/6 h darkness, STD: standard chow diet, CAF: cafeteria diet.

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