Fig. 1 | Scientific Reports

Fig. 1

From: Altered functional brain connectivity, efficiency, and information flow associated with brain fog after mild to moderate COVID-19 infection

Fig. 1

Hypo-connected functional connectome edges. Network-based statistic (NBS) analysis indicated that the COVID-19 group demonstrated significantly lower functional connectivity compared to controls in multiple cortical and subcortical regions across the entire brain, especially the default mode network (mean t = 3.47 ± 0.36, range = 3.1–5.14, p = 0.033, FWE corrected, d = 0.92 to 1.5). The functional connectome is shown here as a graph with spheres representing nodes (regions) and lines representing their functional connections (edges). Nodes are colored by their membership in 1 of 8 functional networks evaluated (see color bar): 1: medial frontal, 2: frontoparietal, 3: default mode, 4: subcortical/cerebellar, 5: motor, 6: visual 1, 7: visual 2, 8: visual association (there were no significant differences in network 4). There were no regions of significant hyper-connectivity.

Back to article page